Description

2-[15N]Acetamido-2-Deoxy-D-Glucose is a stable isotope-labeled derivative of N-acetylglucosamine, where the nitrogen atom in the acetamido group is enriched with the 15N isotope. This compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracking and quantification in complex biological systems. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, proteomics, glycobiology, and metabolic pathway analysis.

Application

• Metabolic Flux Analysis (MFA): Used as a 15N-labeled tracer to study glucose metabolism, glycosylation pathways, and amino sugar biosynthesis in cell cultures and model organisms.
• Glycoprotein & Proteomics Research: Serves as a precursor for the synthesis of isotopically labeled glycans and glycopeptides for mass spectrometry-based structural and functional studies.
• Pharmaceutical R&D: Employed in the development and testing of novel therapeutics targeting metabolic disorders, cancer metabolism, and infectious diseases.
• Biochemical Assay Standards: Acts as an internal standard in quantitative LC-MS and NMR assays to ensure accuracy and reproducibility in analytical measurements.
• Enzyme Kinetics Studies: Utilized to investigate the mechanisms and kinetics of enzymes involved in carbohydrate metabolism, such as hexokinases and glycosyltransferases.
• Nutritional Science Research: Applied in studies examining the metabolism of amino sugars and their role in joint health and inflammation.

Basic Information

Item	Detail
Product Name	2-[15N]Acetamido-2-Deoxy-D-Glucose
CAS No.	478518-85-3
Molecular Formula	C8H1515NO6
Molecular Weight	Contact for details
Synonyms	2-Acetamido-2-deoxy-D-glucose-15N; N-Acetyl-15N-D-glucosamine; GlcNAc-15N; (2R,3R,4R,5S,6R)-3-Acetamido-15N-6-(hydroxymethyl)oxane-2,4,5-triol; 2-(15N)Acetamido-2-deoxy-D-glucopyranose; N-Acetyl-15N-β-D-glucosamine; Stable Isotope Labeled N-Acetylglucosamine
EINECS	Contact for details

Quality Control

Every batch of 2-[15N]Acetamido-2-Deoxy-D-Glucose is produced and analyzed under strict quality protocols to ensure the highest isotopic and chemical purity for research applications. Our quality assurance includes verification of isotopic enrichment (Atom % 15N) and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific analytical data (including NMR and MS confirmation) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Enrichment (Atom % 15N)	≥ 98%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.