Description

2-Acetamido-2-Deoxy-D-[Ul-13C6]Glucose is a uniformly carbon-13 labeled derivative of N-acetylglucosamine, a fundamental building block in glycobiology and metabolic research. This stable isotope-labeled compound is essential for advanced analytical techniques, providing critical insights into biochemical pathways and structural elucidation. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as metabolic flux analysis, NMR spectroscopy, and mass spectrometry-based proteomics.

Application

• Metabolic Pathway Tracing: Serves as a crucial tracer in 13C metabolic flux analysis (13C-MFA) to study carbohydrate metabolism in cells and microorganisms.
• Biomolecular NMR Spectroscopy: Used as an isotopic label to enhance signal resolution and sensitivity in structural studies of glycoproteins, glycolipids, and complex carbohydrates.
• Mass Spectrometry Standards: Acts as an internal standard for the accurate quantification of N-acetylglucosamine and related metabolites via LC-MS or GC-MS.
• Glycobiology Research: Enables the study of glycosylation processes, enzyme kinetics, and the biosynthesis of hyaluronic acid, chitin, and other glycopolymers.
• Pharmaceutical Development: Supports drug discovery efforts targeting metabolic disorders, infectious diseases, and cancer by elucidating sugar-nucleotide pathways.
• Diagnostic Reagent Manufacturing: Incorporated into the production of high-precision diagnostic kits and assays for clinical research.

Basic Information

Product Name	2-Acetamido-2-Deoxy-D-[Ul-13C6]Glucose
CAS No.	478518-83-1
Molecular Formula	C136H15NO6
Molecular Weight	~225.18 g/mol (13C-labeled)
Synonyms	N-Acetyl-D-[U-13C6]glucosamine; [U-13C6]-N-Acetylglucosamine; 2-Acetamido-2-deoxy-D-glucose-13C6; GlcNAc-13C6; NAG-13C6; (2R,3R,4R,5S,6R)-5-Acetamido-2-(hydroxymethyl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-3,4-diol-13C6; 2-(Acetylamino)-2-deoxy-D-glucose-13C6
EINECS	Contact for details

Quality Control

Every batch of our 13C-labeled N-Acetylglucosamine is manufactured and analyzed under strict quality systems to ensure exceptional isotopic and chemical purity for research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity, and specific analytical results. Our quality commitment aligns with the standards expected for high-value biochemical reagents used in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (HPLC)	≥98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.