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α-D-[1-13C]Galactopyranosyl 1-Phosphate Dipotassium Salt CAS NO 478518-78-4
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CAS No.:478518-78-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
α-D-[1-13C]Galactopyranosyl 1-Phosphate Dipotassium Salt is a high-purity, isotopically labeled biochemical reagent essential for advanced metabolic and enzymatic research. This compound serves as a critical, stable-isotope labeled substrate for tracing galactose metabolism and studying the mechanisms of enzymes like galactose-1-phosphate uridylyltransferase. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and diagnostic developers focused on inborn errors of metabolism, such as Galactosemia, and carbohydrate pathway analysis.
Application
- Metabolic Pathway Tracing: Used as a 13C-labeled tracer in NMR and mass spectrometry studies to elucidate galactose metabolic fluxes and kinetics.
- Enzyme Kinetics & Inhibition Studies: Serves as a key substrate for assaying the activity and inhibition of galactose-1-phosphate uridylyltransferase (GALT) and related enzymes.
- Biomedical Research on Galactosemia: Critical for developing and validating diagnostic assays and researching therapeutic interventions for Galactosemia and related disorders.
- Glycobiology & Glycan Synthesis: Acts as a building block in the enzymatic synthesis of complex, isotopically labeled oligosaccharides and glycoconjugates.
- Stable Isotope-Labeled Standard (SILS): Employed as an internal standard in LC-MS/MS and GC-MS for the accurate quantification of galactose-1-phosphate in biological samples.
- Pharmaceutical Development: Used in drug discovery programs targeting carbohydrate-processing enzymes for metabolic diseases and cancer.
Basic Information
| Product Name | α-D-[1-13C]Galactopyranosyl 1-Phosphate Dipotassium Salt |
| CAS No. | 478518-78-4 |
| Molecular Formula | C6H1113CO9P·2K |
| Molecular Weight | Contact for details |
| Synonyms | 1-13C-Galactose-1-phosphate dipotassium salt; [1-13C]-α-D-Galactopyranosyl 1-phosphate dipotassium salt; α-D-Galactopyranosyl 1-phosphate (1-13C) dipotassium; Galactose-1-phosphate (1-13C) K2 salt; α-D-[1-13C]Gal-1-P (dipotassium); Labeled Gal-1-P; G1P (1-13C) dipotassium salt; Isotopically labeled galactose-1-phosphate |
| EINECS | Contact for details |
Quality Control
Every batch of our α-D-[1-13C]Galactopyranosyl 1-Phosphate Dipotassium Salt is manufactured and tested under strict quality systems to ensure exceptional isotopic and chemical purity for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC/NMR), and identity confirmation. Our quality commitment aligns with the standards required for pharmaceutical and diagnostic research.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to ensure long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (NMR) | Conforms to structure |
| Identification (MS) | Conforms to structure |
| 13C Isotopic Enrichment | ≥ 99 atom % |
| Purity (HPLC) | ≥ 98% |
| Chemical Purity (NMR) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| pH (in solution) | 6.0 - 8.0 |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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