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D-[6-13C]Galactose CAS NO 478518-62-6
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CAS No.:478518-62-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-[6-13C]Galactose is a stable isotope-labeled analog of the essential monosaccharide D-galactose, where the carbon-13 isotope is specifically incorporated at the C-6 position. This high-purity labeled compound is critical for advanced metabolic research, enabling precise tracking and quantification of galactose pathways using techniques like Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS). It is an indispensable tool for researchers and manufacturers in pharmaceutical development, clinical diagnostics, and nutritional studies, particularly for investigating inborn errors of metabolism such as galactosemia.
Application
- Metabolic Flux Analysis (MFA): Used as a tracer to map and quantify the galactose metabolic network in cell cultures, tissues, and whole organisms.
- Drug Metabolism & Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS/MS and GC-MS assays for the accurate bioanalysis of galactose and related metabolites in preclinical and clinical studies.
- Diagnostic Reagent Manufacturing: A key component in the production of calibrated standards and reagents for clinical diagnostic kits targeting metabolic disorders.
- Biomedical Research: Facilitates studies on carbohydrate metabolism, glycosylation disorders, cancer cell energetics, and liver function.
- Nutritional Science: Enables research into lactose/galactose digestion, infant formula metabolism, and the role of prebiotics.
- NMR Spectroscopy: Provides a sensitive probe for structural and dynamic studies of galactose-binding proteins, enzymes, and complex carbohydrates.
Basic Information
| Product Name | D-[6-13C]Galactose |
| CAS No. | 478518-62-6 |
| Molecular Formula | C512C13H12O6 |
| Molecular Weight | 181.15 g/mol (for 13C1) |
| Synonyms | (6-13C)-D-Galactose; D-Galactose-6-13C; 6-13C-Labeled D-Galactose; Galactose (D-, [6-13C]); [6-13C]-D-Galactopyranose; 13C Labeled Galactose; Stable Isotope-Labeled Galactose; 478518-62-6 |
| EINECS | Contact for details |
Quality Control
Every batch of D-[6-13C]Galactose is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and MS to confirm isotopic enrichment at the specified position. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, isotopic enrichment, and specific tests. Our quality commitment ensures the material meets the stringent requirements for research and in-vitro diagnostic (IVD) use.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Isotopic Enrichment | ≥ 99 atom % 13C |
| Isotopic Purity (13C NMR) | ≥ 99% at C-6 |
| Water Content (KF) | ≤ 1.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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