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D-[4-13C]Galactose CAS NO 478518-58-0
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CAS No.:478518-58-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
D-[4-13C]Galactose is a stable isotope-labeled analog of the monosaccharide galactose, specifically enriched with carbon-13 at the 4-position. This high-purity labeled compound is essential for advanced metabolic research, enabling precise tracking and quantification of galactose pathways in biological systems. It is a critical reagent for scientists in pharmaceutical development, clinical diagnostics, and nutritional research who require accurate tracer studies and metabolic flux analysis.
Application
- Metabolic Flux Analysis (MFA): Used as a 13C tracer to map and quantify intracellular metabolic pathways in microbial, plant, and mammalian cell cultures.
- Drug Metabolism & Pharmacokinetics (DMPK): Serves as an internal standard in LC-MS and GC-MS for the accurate quantification of galactose and its metabolites in biological matrices.
- Clinical Research: Employed in studies of inborn errors of metabolism, such as Galactosemia, to investigate disorder mechanisms and potential therapeutic interventions.
- Nutritional Science: Facilitates research into galactose absorption, utilization, and its role in lactose metabolism and gut microbiome studies.
- Biomarker Discovery: Aids in the development of stable isotope dilution assays for potential diagnostic biomarkers related to carbohydrate metabolism disorders.
- NMR Spectroscopy: Provides a distinct 13C-NMR signal for structural elucidation and dynamic studies of glycans and glycoconjugates.
Basic Information
| Item | Detail |
|---|---|
| Product Name | D-[4-13C]Galactose |
| CAS No. | 478518-58-0 |
| Molecular Formula | C513CH12O6 |
| Molecular Weight | 181.15 g/mol (for 13C1 isotopologue) |
| Synonyms | D-Galactose-4-13C; (4-13C)Galactose; 4-13C-Galactose; Galactose-4-13C; D-Galactose (4-13C); [4-13C]-D-Galactose; 13C Labeled D-Galactose; Stable Isotope Labeled Galactose |
| EINECS | Contact for details |
Quality Control
Every batch of D-[4-13C]Galactose is manufactured and analyzed under strict quality protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and Mass Spectrometry to confirm labeling position and enrichment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and analytical results.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98% |
| Isotopic Enrichment | ≥ 99 atom % 13C |
| Isotopic Purity (13C NMR) | ≥ 98% at C-4 |
| Water Content (KF) | ≤ 1.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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