Description

6-Deoxy-L-[6-13C]Galactose is a stable isotope-labeled derivative of 6-deoxy-L-galactose (L-fucose), where the carbon-6 position is enriched with the non-radioactive carbon-13 isotope. This compound is a critical tool for advanced metabolic research and analytical method development, providing a precise tracer for studying biochemical pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, isotopically labeled standards for mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Metabolic Pathway Tracing: Used as a stable isotope-labeled internal standard in mass spectrometry to quantitatively track the metabolism of L-fucose and related glycans in biological systems.
• NMR Spectroscopy Studies: Serves as a probe for structural and dynamic studies of carbohydrate-protein interactions and enzymatic mechanisms due to the 13C label.
• Pharmaceutical R&D: Essential in the development and validation of bioanalytical methods for novel therapeutics targeting glycosylation disorders or cancer biomarkers.
• Diagnostic Assay Development: Employed in calibrating high-sensitivity clinical assays, such as those for congenital disorders of glycosylation (CDG).
• Glycobiology Research: Facilitates detailed investigation into fucosylation processes, which are crucial in cell signaling, immune response, and pathogen recognition.
• Quality Control & Reference Standard: Acts as a certified reference material (CRM) for ensuring accuracy and precision in analytical laboratories.

Basic Information

Product Name	6-Deoxy-L-[6-13C]Galactose
CAS No.	478518-51-3
Molecular Formula	C512C13CH12O5
Molecular Weight	165.14 g/mol (for 13C1 isotopologue)
Synonyms	L-[6-13C]Fucose; 6-Deoxy-L-galactose-6-13C; (2S,3S,4S,5R)-6-Methyl-6-13C-tetrahydro-2H-pyran-2,3,4,5-tetraol; 13C1-L-Fucose; Isotopically Labeled L-Fucose; 6-13C-L-Fuc; Stable Isotope-Labeled 6-Deoxygalactose
EINECS	Contact for details

Quality Control

Every batch of 6-Deoxy-L-[6-13C]Galactose is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for research applications. Our quality commitment includes comprehensive analytical testing via NMR, HPLC, and MS to verify isotopic enrichment, chemical identity, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data including assay, isotopic purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment (MS)	≥ 99% at position 6
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.