Description

2-Deoxy-D-[1-13C]Erythro-Pentose is a stable isotope-labeled derivative of 2-deoxy-D-ribose, a fundamental sugar moiety in DNA, where the carbon-1 position is enriched with the 13C isotope. This precise labeling is critical for advanced research in nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), enabling detailed metabolic pathway tracing and structural elucidation studies. It is an essential tool for researchers and developers in pharmaceutical discovery, biochemistry, and metabolomics who require high-purity, isotopically defined building blocks for their investigative work.

Application

• NMR Spectroscopy Tracer: Used as a 13C-labeled precursor for tracking the biosynthesis and metabolic fate of nucleosides and nucleic acids in complex biological systems.
• Mass Spectrometry Internal Standard: Serves as a critical internal standard for the accurate quantification of deoxyribose and related metabolites via LC-MS or GC-MS methodologies.
• Pharmaceutical Research & Development: Employed in the synthesis and study of labeled nucleoside analogs for antiviral and anticancer drug development.
• Biochemical Pathway Analysis: Facilitates the mapping of pentose phosphate pathway and nucleotide salvage pathway dynamics in cellular metabolism studies.
• Stable Isotope Probing (SIP): Applied in environmental and microbiological research to study microbial communities that metabolize DNA components.
• Academic Research: A key reagent for universities and research institutes conducting fundamental studies in glycobiology and chemical biology.

Basic Information

Product Name	2-Deoxy-D-[1-13C]Erythro-Pentose
CAS No.	478511-57-8
Molecular Formula	C5H1013CO4
Molecular Weight	135.12 g/mol (for 13C1 isotopologue)
Synonyms	2-Deoxy-D-[1-13C]ribose; 1-13C-2-Deoxy-D-ribose; 2-Deoxy-D-erythro-pentose-1-13C; [1-13C]-2-Deoxy-D-ribose; 2-Deoxy-D-ribose-1-13C; Stable Isotope Labeled 2-Deoxyribose; 2-Deoxy-D-[1-13C]pentose; DNA Sugar-13C Tracer
EINECS	Contact for details

Quality Control

Every batch of 2-Deoxy-D-[1-13C]Erythro-Pentose is produced and analyzed under strict quality protocols to ensure isotopic and chemical purity for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as isotopic enrichment, chemical purity, and absence of critical impurities. Our quality systems are designed to support compliance with the rigorous standards required for pharmaceutical research (GLP) and analytical reagent applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C NMR)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.