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6-Deoxy-L-[3-13C]Mannose Monohydrate CAS NO 478511-54-5
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CAS No.:478511-54-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Deoxy-L-[3-13C]Mannose Monohydrate is a stable isotope-labeled derivative of the monosaccharide 6-deoxy-L-mannose, specifically enriched with carbon-13 at the C-3 position. This high-purity labeled compound is essential for advanced metabolic flux analysis and tracer studies, providing critical insights into biochemical pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate metabolism research, drug development, and the synthesis of isotopically labeled glycoconjugates.
Application
- Metabolic Tracer Studies: Used in 13C NMR spectroscopy and mass spectrometry to trace and quantify metabolic fluxes in biological systems.
- Drug Discovery & Development: Serves as a key intermediate in the synthesis of isotopically labeled drug candidates for pharmacokinetic and metabolic stability studies.
- Biochemical Research: Enables detailed investigation of L-rhamnose and other deoxy sugar metabolic pathways in bacteria, plants, and humans.
- Glycobiology: Used in the preparation of 13C-labeled glycans and glycoconjugates for structural and functional analysis.
- Analytical Standard: Acts as a certified reference standard for quantitative analysis in complex biological matrices.
- Nutritional Science: Applied in studies examining the metabolism and utilization of rare sugars.
Basic Information
| Product Name | 6-Deoxy-L-[3-13C]Mannose Monohydrate |
| CAS No. | 478511-54-5 |
| Molecular Formula | C6H1213CO5 • H2O |
| Molecular Weight | 181.15 g/mol (for 13C1 isotopologue) |
| Synonyms | L-[3-13C]Rhamnose Monohydrate; 6-Deoxy-L-[3-13C]mannopyranose Monohydrate; (3-13C)-6-Deoxy-L-mannose Monohydrate; Isotope-labeled L-Rhamnose; 13C1-L-Rhamnose; 6-Deoxy-L-mannose-3-13C Monohydrate; L-Rhamnose-3-13C |
| EINECS | Contact for details |
Quality Control
Every batch of 6-Deoxy-L-[3-13C]Mannose Monohydrate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment. Our quality assurance protocols are designed to meet the stringent requirements of research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and specific tests is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Isotopic Enrichment (13C) | ≥ 99 atom % |
| Water Content (KF) | 4.0 - 8.0 % |
| Specific Optical Rotation | Contact for details |
| Residue on Ignition | ≤ 0.1 % |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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