Description

6-Deoxy-L-[1-13C]Mannose Monohydrate is a stable isotope-labeled derivative of the monosaccharide 6-deoxy-L-mannose, where the carbon-1 position is enriched with the non-radioactive 13C isotope. This compound is a critical tool for advanced metabolic research and analytical method development, providing a precise tracer for studying biochemical pathways. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic developers in the fields of nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and isotopic labeling studies.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in NMR and MS-based studies to elucidate biosynthetic routes and flux analysis in microbial, plant, and mammalian systems.
• Biomarker Research: Serves as an internal standard for the accurate quantification of deoxy sugars and related metabolites in complex biological samples.
• Glycobiology Studies: Employed in the research of rare deoxy-sugars involved in glycoconjugate synthesis and bacterial cell wall components.
• Pharmaceutical Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for compounds containing or metabolizing to deoxy-sugar moieties.
• Diagnostic Reagent Synthesis: Acts as a labeled precursor in the synthesis of specialized reagents for clinical diagnostics and imaging.
• Stable Isotope Labeling: A key building block for the preparation of more complex, site-specifically 13C-labeled oligosaccharides and natural products.

Basic Information

Product Name	6-Deoxy-L-[1-13C]Mannose Monohydrate
CAS No.	478511-48-7
Molecular Formula	C513CH12O5 • H2O
Molecular Weight	182.15 g/mol (for major isotopologue)
Synonyms	L-(1-13C)-6-Deoxymannose Monohydrate; 6-Deoxy-L-mannose-1-13C Monohydrate; L-Rhamnose-1-13C (6-deoxy-L-mannose-1-13C) Monohydrate; 13C Labeled 6-Deoxy-L-mannose; [1-13C]-6-Deoxy-L-mannose Hydrate; Isotopic Tracer for Rhamnose Metabolism; 6-Deoxy-L-[1-13C]mannose Hydrate
EINECS	Contact for details

Quality Control

Every batch of 6-Deoxy-L-[1-13C]Mannose Monohydrate is produced and analyzed under strict quality systems. We ensure high chemical purity and isotopic enrichment through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific data on purity, isotopic abundance, and identity confirmation. Our quality commitment supports research requiring reproducible and reliable isotopic standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure and labeling position
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Isotopic Enrichment	≥ 99 atom % 13C at C-1
Water Content (KF)	4.0 - 9.0 % (theoretical for monohydrate: ~9.0%)
Specific Optical Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.