Description

[3'-13C]2'-Deoxyuridine is a stable isotope-labeled nucleoside analog, specifically deuterated at the 3' carbon position. This precise labeling is critical for advanced analytical applications, providing a reliable internal standard for mass spectrometry to ensure accurate quantification and metabolic pathway tracing. It is an essential research tool for scientists in pharmaceutical development, clinical diagnostics, and biochemistry who require high-fidelity isotopic standards for pharmacokinetic studies, biomarker discovery, and nucleic acid metabolism research.

Application

• Mass Spectrometry Internal Standard: Serves as a critical quantitative reference in LC-MS/MS and GC-MS analyses for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used in tracer studies to investigate the synthesis and catabolism of pyrimidine nucleotides and DNA in cellular systems.
• Biomedical Research: Facilitates research into antiviral and anticancer mechanisms, particularly for compounds targeting thymidine metabolism.
• Clinical Diagnostic Assay Development: Employed in the development and validation of high-sensitivity assays for measuring nucleoside analogs in biological matrices.
• Isotope Dilution Analysis: Provides the foundation for accurate and precise quantification of endogenous 2'-deoxyuridine and related metabolites in complex samples.
• Pharmaceutical Quality Control: Used in the analysis and stability testing of nucleoside-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	[3'-13C]2'-Deoxyuridine
CAS No.	478510-89-3
Molecular Formula	C9H1213CN2O5
Molecular Weight	Contact for details
Synonyms	1-(2-Deoxy-β-D-ribofuranosyl)-[3'-13C]uracil; [3'-13C]dU; 2'-Deoxy-[3'-13C]uridine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-[3'-13C]-2,4(1H,3H)-pyrimidinedione; Isotopically Labeled 2'-Deoxyuridine; 13C-Labeled dUrd; Stable Isotope-Labeled Nucleoside
EINECS	Contact for details

Quality Control

Our [3'-13C]2'-Deoxyuridine is manufactured under strict quality systems to ensure isotopic and chemical purity for demanding research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >99 atom % 13C), chemical purity (by HPLC), and identity confirmation. We adhere to industry best practices for analytical reference materials, ensuring traceability and reliability for your critical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	>99 atom % 13C
Chemical Purity (HPLC)	≥98%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.