Description

[1'-13C]2'-Deoxyuridine is a stable isotope-labeled nucleoside analog, specifically deuterated at the 1' carbon position. This precise labeling is critical for advanced analytical applications, providing a reliable internal standard for mass spectrometry and enabling detailed metabolic pathway studies. It is an essential research tool for pharmaceutical development, clinical diagnostics, and academic research in biochemistry and molecular biology.

Application

• Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS/MS and GC-MS analysis for pharmacokinetic and bioanalytical studies.
• Metabolic Pathway Tracing: Enables the investigation of nucleoside metabolism, DNA synthesis, and salvage pathways in cell culture and in vivo models.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates the accurate quantification of unlabeled 2'-deoxyuridine and related metabolites in biological matrices.
• Biomedical Research: Supports studies in oncology and virology, particularly related to cell proliferation and the mechanism of action of antiviral or anticancer nucleoside analogs.
• Diagnostic Assay Development: Serves as a key component in the development of high-sensitivity clinical diagnostic tests for metabolic disorders.

Basic Information

Product Name	[1'-13C]2'-Deoxyuridine
CAS No.	478510-85-9
Molecular Formula	C9H1213CN2O5
Molecular Weight	229.19 g/mol (for 13C1 isotopologue)
Synonyms	1'-Carbon-13 Labeled 2'-Deoxyuridine; 1'-(13)C-2'-Deoxyuridine; [1'-13C]dU; 2'-Deoxy[1'-13C]uridine; 1'-13C-2'-Deoxyuridine; Uridine, 2'-deoxy-, 1'-13C-labeled; Stable Isotope Labeled dU; 1'-13C-dUrd
EINECS	Contact for details

Quality Control

Every batch of [1'-13C]2'-Deoxyuridine is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive analytical data provided. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity (by HPLC), and identity confirmation (by NMR and MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.