Description

L-[5-13C]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, where the carbon-13 isotope is specifically incorporated at the C-5 position. This compound is essential for advanced metabolic research, providing a critical tracer for studying carbohydrate metabolism, pentose phosphate pathway flux, and gut microbiome function using techniques like Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic developers engaged in isotope-based studies, metabolic flux analysis, and the development of clinical diagnostic tests.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C tracer to quantify intracellular metabolic pathway rates and network regulation in microbial, plant, and mammalian systems.
• NMR Spectroscopy Studies: Serves as a specific probe for investigating the structure, dynamics, and metabolic fate of xylose and its derivatives in complex biological matrices.
• Mass Spectrometry (MS) Standards: Acts as an internal standard for the accurate quantification of D-xylose in biofluids, cell cultures, and fermentation broths via LC-MS or GC-MS, enhancing analytical precision.
• Gut Microbiome & Digestive Research: Employed to trace the fermentation pathways of dietary fibers and prebiotics by gut microbiota, linking specific bacterial metabolism to host health outcomes.
• Pharmaceutical R&D: Facilitates drug metabolism studies for compounds affecting carbohydrate metabolism and supports the development of diagnostic agents for disorders like carbohydrate malabsorption.
• Biotechnological Process Optimization: Applied in metabolic engineering to trace and optimize xylose utilization pathways in microorganisms for biofuel and biochemical production.

Basic Information

Product Name	L-[5-13C]Xylose
CAS No.	478506-64-8
Molecular Formula	C5H10O5 (with 13C at position 5)
Molecular Weight	151.13 g/mol (for 13C labeled form)
Synonyms	L-(5-13C)Xylose
Xylose-5-13C (L-form)
(5-13C)-L-Xylose
L-Xylose (5-13C)
L-Xylopyranose-5-13C
Stable Isotope Labeled L-Xylose
13C-Labeled L-Xylose
EINECS	Contact for details

Quality Control

Our L-[5-13C]Xylose is produced and handled under strict quality protocols to ensure the highest isotopic and chemical purity for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (atom % 13C), chemical purity, and specific analytical data from NMR and HPLC. We adhere to relevant standards for research-grade biochemicals, ensuring reliability and consistency for your isotopic tracing experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.