Description

D-[2-13C]Tagatose is a stable isotope-labeled analog of the rare ketohexose sugar, D-tagatose, specifically enriched with carbon-13 at the C-2 position. This precise isotopic labeling makes it an indispensable tool for advanced metabolic and biochemical research, enabling accurate tracing and quantification in complex biological systems. It is primarily utilized by research scientists and analytical laboratories in the pharmaceutical, nutritional science, and biotechnology sectors for applications such as metabolic flux analysis, drug metabolism studies, and the development of diagnostic assays.

Application

• Metabolic Pathway Tracing: Used as a tracer in in vitro and in vivo studies to elucidate sugar metabolism and glycolytic fluxes.
• Drug Metabolism Studies (DMPK): Serves as an internal standard in LC-MS and GC-MS for the quantitative analysis of tagatose and related metabolites in pharmacokinetic research.
• Nutritional Research: Enables the study of the absorption, distribution, and metabolic fate of tagatose as a low-calorie sweetener in human and animal models.
• Biochemical Assay Development: Acts as a calibrated reference standard for validating analytical methods in clinical and food testing laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-accuracy quantification in complex matrices for quality control and regulatory compliance testing.
• Stable Isotope Probing (SIP): Facilitates the study of microbial communities and their functional roles in environmental and gut microbiome research.

Basic Information

Product Name	D-[2-13C]Tagatose
CAS No.	478506-44-4
Molecular Formula	C513CH12O6
Molecular Weight	181.15 g/mol (for 13C1 labeled form)
Synonyms	(2-13C)-D-Tagatose; D-Tagatose-2-13C; 1,3,4,5,6-Pentahydroxy-2-13C-hexan-2-one; 13C Labeled D-Tagatose; [2-13C]-Tagatose; Tagatose-2-13C; Isotopically Labeled Tagatose
EINECS	Contact for details

Quality Control

Every batch of D-[2-13C]Tagatose is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and isotopic enrichment meet the exacting standards required for research use. Comprehensive testing includes NMR and MS for isotopic purity and chemical identity, and HPLC for chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for isotopic enrichment, chemical purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.