Description

L-[5-13C]Sorbose is a stable isotope-labeled analog of L-sorbose, a key sugar intermediate, where the carbon-13 isotope is specifically incorporated at the 5-position. This precise labeling is critical for advanced metabolic and biochemical research, providing a non-radioactive tracer for accurate pathway analysis. It is an essential material for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require high-fidelity isotopic standards for mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies.

Application

• Metabolic Pathway Tracing: Used as a stable isotope tracer in in vivo and in vitro studies to elucidate the biosynthesis and catabolism of ascorbic acid (Vitamin C) and other metabolic routes.
• Pharmaceutical Research & Development: Serves as a critical labeled precursor in the research and synthesis of isotopically labeled drug candidates and active pharmaceutical ingredients (APIs).
• Quantitative Mass Spectrometry (MS): Employed as an internal standard for the precise and accurate quantification of L-sorbose and related metabolites in complex biological matrices.
• NMR Spectroscopy: Provides a distinct 13C-NMR signal for structural elucidation and dynamic studies of carbohydrate-containing molecules.
• Biochemical Assay Development: Utilized in the development of diagnostic assays and enzymatic studies where tracking specific carbon atoms is necessary.
• Nutritional Science Research: Applied in studies investigating sugar metabolism, bioavailability, and the biochemical fate of dietary components.

Basic Information

Product Name	L-[5-13C]Sorbose
CAS No.	478506-36-4
Molecular Formula	C6H12O6 (with 13C at position 5)
Molecular Weight	~181.15 g/mol (exact mass depends on 13C enrichment)
Synonyms	(5-13C)-L-Sorbose; L-Sorbose-5-13C; 5-13C-L-Sorbose; Isotopically Labeled L-Sorbose; [5-13C]Sorbose; Stable Isotope-Labeled Sorbose; Carbon-13 Labeled Sorbose; L-(-)-Sorbose-5-13C
EINECS	Contact for details

Quality Control

Our L-[5-13C]Sorbose is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), and specific optical rotation. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	13C-NMR signal consistent with labeling at position 5
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.