Description

4-(Bromomethyl)-2-Fluorobenzoicacid is a high-purity fluorinated aromatic building block with a reactive bromomethyl handle. This compound is critical for the synthesis of complex molecules, offering a versatile point for further functionalization in advanced chemical processes. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated aromatic structures.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated components in electronic display and lighting technologies.
• Cross-Coupling Reactions: The bromomethyl group facilitates Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions for carbon-carbon bond formation.
• Peptide Mimetics & Bioconjugation: Useful for introducing fluorinated benzoic acid motifs into peptides or for creating linker molecules in bioconjugation chemistry.
• Polymer Modification: Employed to incorporate fluorinated aromatic units into specialty polymers to alter thermal, chemical, or surface properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and fluorinated compound libraries.

Basic Information

Product Name	4-(Bromomethyl)-2-Fluorobenzoicacid
CAS No.	477199-77-2
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-Fluoro-4-(bromomethyl)benzoic Acid; 4-Bromomethyl-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-4-(bromomethyl)-; 2-Fluoro-4-bromomethylbenzoic Acid; 4-(Bromomethyl)-2-fluorobenzoic Acid; 2-Fluoro-4-(bromomethyl)benzoic acid; 4-Bromomethyl-2-fluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2-Fluorobenzoicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.