Description

Selexipag is a potent, orally active, non-prostanoid prostacyclin (IP) receptor agonist. This compound is of significant interest in the pharmaceutical industry for its targeted mechanism of action. It is primarily utilized in the research and development of treatments for pulmonary arterial hypertension (PAH).

Application

• Active Pharmaceutical Ingredient (API) in the formulation of oral medications for pulmonary arterial hypertension (PAH).
• Key intermediate in advanced pharmaceutical synthesis and process development.
• Reference standard for analytical method development and validation in quality control laboratories.
• Biochemical research tool for studying prostacyclin (IP) receptor signaling pathways.
• Pre-clinical and clinical research studies investigating cardiovascular pharmacology.

Basic Information

Product Name	Selexipag
CAS No.	475086-01-2
Molecular Formula	C26H32N4O4S
Molecular Weight	496.62 g/mol
Synonyms	2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide; ACT-293987; NS-304; Uptravi (brand name); 2-[4-[(5,6-Diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methanesulfonylacetamide
EINECS	Contact for details

Quality Control

Our Selexipag is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure high purity and consistency, meeting standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.