Description

N,n-Dimethyl Sphingosine (D17:1) is a chemically modified, high-purity sphingolipid derivative, specifically a dimethylated form of sphingosine with a 17-carbon chain and one double bond. This compound is a critical biochemical tool and intermediate for advanced life science research, particularly in the study of sphingolipid metabolism and cell signaling pathways. It is essential for researchers and manufacturers in pharmaceutical R&D, academic biochemistry, and the development of novel lipid-based therapeutics and diagnostic agents.

Application

• Biochemical Research: A key reference standard and inhibitor for studying sphingosine kinase (SphK) activity and the sphingolipid rheostat in cellular processes.
• Pharmaceutical Development: Serves as a sophisticated intermediate in the synthesis of novel therapeutic agents targeting cancer, inflammation, and immune disorders.
• Cell Signaling Studies: Used to investigate the role of sphingolipid metabolites in apoptosis, proliferation, and stress responses.
• Metabolic Pathway Analysis: Employed as a probe to elucidate complex sphingolipid metabolic networks in model organisms and cell lines.
• Lipidomics: An essential analytical standard for the accurate identification and quantification of sphingolipids in mass spectrometry-based lipidomic profiling.
• Enzyme Assay Development: Utilized as a substrate or inhibitor in high-throughput screening assays for drug discovery targeting lipid-modifying enzymes.

Basic Information

Product Name	N,n-Dimethyl Sphingosine (D17:1)
CAS No.	474943-92-5
Molecular Formula	C19H39NO2
Molecular Weight	313.52 g/mol
Synonyms	DMS (D17:1); N,N-Dimethylsphingosine (17:1); (2S,3R,4E)-2-Dimethylamino-4-octadecene-1,3-diol; (E)-2-(Dimethylamino)-4-octadecene-1,3-diol; D-erythro-N,N-Dimethylsphingosine (C17); Sphingosine, N,N-dimethyl-, (E)-; Lipid research compound 474943-92-5
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl Sphingosine (D17:1) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided, confirming identity, purity, and conformity to our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.