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1,2-Dihexanoyl-D22-Sn-Glycero-3-Phosphocholine-1,1,2,2-D4-N,N,n-Trimethyl-D9 CAS NO 474942-76-2
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CAS No.:474942-76-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dihexanoyl-D22-Sn-Glycero-3-Phosphocholine-1,1,2,2-D4-N,N,n-Trimethyl-D9 CAS NO 474942-76-2 is a high-purity, multi-deuterated phospholipid analog, specifically designed for advanced research and analytical applications. This compound is critical for studies requiring precise isotopic labeling to track metabolic pathways, investigate membrane dynamics, and serve as an internal standard in mass spectrometry. It is an essential tool for researchers and scientists in pharmaceutical development, lipidomics, and structural biology.
Application
- Mass Spectrometry Internal Standard: Used as a quantitative reference standard in LC-MS/MS and other mass spectrometry techniques for accurate lipid quantification.
- Metabolic Tracing Studies: Enables detailed investigation of phospholipid metabolism, biosynthesis, and turnover in biological systems using deuterium labeling.
- Membrane Biophysics Research: Serves as a probe for studying lipid bilayer properties, phase behavior, and protein-lipid interactions with minimal interference from proton signals in NMR.
- Pharmaceutical R&D: Utilized in the development and validation of analytical methods for lipid-based drug formulations and delivery systems.
- Lipidomics and Biomarker Discovery: Facilitates the precise identification and measurement of phosphatidylcholine species in complex biological samples.
- Chemical Biology Probes: Acts as a building block for creating labeled probes to visualize and track cellular processes.
Basic Information
| Item | Details |
|---|---|
| Product Name | 1,2-Dihexanoyl-D22-Sn-Glycero-3-Phosphocholine-1,1,2,2-D4-N,N,n-Trimethyl-D9 |
| CAS No. | 474942-76-2 |
| Molecular Formula | C26D35H14NO8P |
| Molecular Weight | ~556.6 g/mol (deuterated form) |
| Synonyms | 1,2-Dihexanoyl-sn-glycero-3-phosphocholine (d35); Deuterated DPPC-d35; 1,2-Dihexanoylphosphatidylcholine-d35; PC(6:0/6:0)-d35; Lyso PC-d35 derivative; Deuterated Phospholipid; 1,2-Dihexanoyl-D22-Sn-Glycero-3-Phosphocholine-1,1,2,2-D4-N,N,n-Trimethyl-D9; Perdeuterated Phosphatidylcholine Analog |
| EINECS | Contact for details |
Quality Control
Every batch of our deuterated phospholipids is manufactured and analyzed under strict quality protocols to ensure the highest isotopic purity and chemical integrity. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm deuterium enrichment and chemical purity, ensuring compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific data for isotopic purity, chemical purity, and identity are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or film |
| Identification (NMR) | Conforms to structure |
| Isotopic Purity (Deuterium Enrichment) | ≥ 98 atom % D |
| Chemical Purity (HPLC) | ≥ 95% |
| Solubility | Soluble in chloroform, methanol, ethanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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