Description

L-Proline, 4-Hydroxy-4-Methyl-, (4S)- (9Ci) is a high-purity, non-proteinogenic amino acid derivative characterized by its unique stereochemistry and functional groups. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients, chiral catalysts, and specialized biochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and peptidomimetic research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor in biochemical assays.
• Catalyst & Ligand Development: Utilized for constructing chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptide Chemistry: Incorporated into custom peptides to study structure-activity relationships or to create peptides with modified backbone properties.

Basic Information

Product Name	L-Proline, 4-Hydroxy-4-Methyl-, (4S)- (9Ci)
CAS No.	459457-01-3
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(4S)-4-Hydroxy-4-methyl-L-proline; 4-Hydroxy-4-methyl-L-proline; (2S,4S)-4-Hydroxy-4-methylpyrrolidine-2-carboxylic acid; 4-Methyl-4-hydroxy-L-proline; L-4-Hydroxy-4-methylproline; 4-Hydroxy-4-methylproline, L-; 4-Hydroxy-4-methyl-(S)-proline
EINECS	Contact for details

Quality Control

Our L-Proline, 4-Hydroxy-4-Methyl-, (4S)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specific impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and potential degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.