Description

1-Naphthalenamine,1,2,3,4-Tetrahydro-5,7-Dimethyl-,(1S)-(9Ci) is a chiral, substituted tetrahydro-naphthalenamine, a valuable intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking high-purity, stereochemically defined building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents, including central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the synthesis of dyes, pigments, and other high-value specialty chemicals.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Naphthalenamine,1,2,3,4-Tetrahydro-5,7-Dimethyl-,(1S)-(9Ci)
CAS No.	459142-40-6
Molecular Formula	C12H17N
Molecular Weight	175.27 g/mol
Synonyms	(1S)-1,2,3,4-Tetrahydro-5,7-dimethyl-1-naphthalenamine; (S)-5,7-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-amine; 1-Naphthalenamine, 1,2,3,4-tetrahydro-5,7-dimethyl-, (1S)-; (S)-1-Amino-5,7-dimethyl-1,2,3,4-tetrahydronaphthalene; 5,7-Dimethyl-1-tetralinamine (S-enantiomer); (1S)-5,7-Dimethyl-1-amino-1,2,3,4-tetrahydronaphthalene; Chiral Tetralin Amine Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Quality is assured through analytical techniques including HPLC, GC, Chiral HPLC, and NMR. Specifications can be tailored to meet cGMP or other stringent regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.