Description

3-Bromo-5-(Trifluoromethoxy)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its bromine and trifluoromethoxy substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, pesticide synthesis, and the creation of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the creation of monomers and functional units for advanced polymers, liquid crystals, and organic semiconductors.
• Chemical Biology Probes: Useful in designing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethoxy)Benzoic Acid
CAS No.	453565-90-7
Molecular Formula	C8H4BrF3O3
Molecular Weight	285.02 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 3-bromo-5-(trifluoromethoxy)-; 5-Bromo-3-(trifluoromethoxy)benzoic acid; 3-Bromo-5-(trifluoromethoxy)benzenecarboxylic acid; CAS 453565-90-7; 3-Br-5-OCF3-C6H3-COOH
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.