Description

3-Fluoro-5-(Methylthio)Benzoic Acid is a high-purity, synthetically valuable benzoic acid derivative distinguished by its fluorine and methylthio substituents. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the introduction of specific functional groups into complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorine and sulfur-containing motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, or organic electronic materials due to its aromatic core and substituents.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	3-Fluoro-5-(Methylthio)Benzoic Acid
CAS No.	453565-64-5
Molecular Formula	C8H7FO2S
Molecular Weight	186.20 g/mol
Synonyms	3-Fluoro-5-(methylsulfanyl)benzoic acid; 5-(Methylthio)-3-fluorobenzoic Acid; Benzoic acid, 3-fluoro-5-(methylthio)-; 3-Fluoro-5-methylmercaptobenzoic acid; 3-Fluoro-5-(methylthio)benzoic acid CAS 453565-64-5; 3-Fluoro-5-(methylsulfanyl)benzoic acid; 3-Fluoro-5-(methylthio)-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Methylthio)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.