Description

Bicyclo[3.1.0]Hexane-2-Methanol, 4-Amino-, (1S,2S,4R,5R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its rigid, fused bicyclic structure and functional handles, which are critical for constructing complex molecular architectures with precise three-dimensional control. Pharmaceutical and agrochemical R&D teams need it as a key intermediate for developing novel active ingredients, particularly in the areas of medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is essential for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that require rigid, functionalized core structures.
• Academic & Industrial R&D: A valuable tool for synthetic chemists in universities and corporate labs exploring new chemical spaces and reaction methodologies.

Basic Information

Item	Details
Product Name	Bicyclo[3.1.0]Hexane-2-Methanol, 4-Amino-, (1S,2S,4R,5R)- (9Ci)
CAS No.	452324-64-0
Molecular Formula	C8H15NO
Molecular Weight	141.21 g/mol
Synonyms	(1S,2S,4R,5R)-4-Aminobicyclo[3.1.0]hexane-2-methanol; (1S,2S,4R,5R)-4-Amino-2-(hydroxymethyl)bicyclo[3.1.0]hexane; 4-Amino-2-(hydroxymethyl)bicyclo[3.1.0]hexane (stereoisomer); Bicyclo[3.1.0]hexane-2-methanol, 4-amino-, (1S,2S,4R,5R)-; Chiral bicyclo[3.1.0]hexane amino alcohol; 452324-64-0; Amino-functionalized bicyclo[3.1.0]hexane derivative.
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-2-Methanol, 4-Amino-, (1S,2S,4R,5R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.