Description

1,3-Benzenediamine, 2-Methyl-5-Nitro-, Labeled With Carbon-14 (9Ci) is a high-specific-activity, isotopically labeled derivative of a key aromatic diamine intermediate. This compound is essential for advanced research and development, particularly in metabolic and pharmacokinetic studies, where precise tracking of molecular pathways is required. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical research facilities, and specialized contract research organizations (CROs) engaged in tracer studies and analytical method development.

Application

• Tracer Studies in Pharmaceutical R&D: Used as a radiolabeled precursor or intermediate to study the absorption, distribution, metabolism, and excretion (ADME) of novel drug candidates.
• Metabolic Pathway Analysis: Enables detailed investigation of biochemical pathways in both mammalian and plant systems for agrochemical and pharmaceutical development.
• Analytical Method Development: Serves as a critical standard for developing and validating sensitive analytical methods, such as Liquid Chromatography-Mass Spectrometry (LC-MS) and accelerator mass spectrometry (AMS).
• Environmental Fate Studies: Employed in research to trace the degradation and environmental behavior of chemical compounds derived from this intermediate.
• Chemical Synthesis Research: Acts as a labeled building block for synthesizing more complex molecules where the fate of the specific carbon atom needs to be monitored.

Basic Information

Product Name	1,3-Benzenediamine, 2-Methyl-5-Nitro-, Labeled With Carbon-14 (9Ci)
CAS No.	449747-92-6
Molecular Formula	C7H9N3O2 (*14C labeled)
Molecular Weight	~167.16 g/mol (unlabeled)
Synonyms	2-Methyl-5-nitro-1,3-benzenediamine-14C; 2-Methyl-5-nitro-m-phenylenediamine-14C; 1,3-Diamino-2-methyl-5-nitrobenzene-14C; 2-Methyl-5-nitrobenzene-1,3-diamine-14C; 5-Nitro-2-methyl-m-phenylenediamine-14C; [14C]-Labeled 2-Methyl-5-nitro-1,3-benzenediamine; Carbon-14 Labeled 2-Methyl-5-nitro-m-phenylenediamine
EINECS	Contact for details

Quality Control

Our radiolabeled compounds are produced and handled under stringent quality control protocols. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as radiochemical purity, chemical purity, specific activity, and solvent composition. We ensure compliance with relevant Good Manufacturing Practice (GMP) guidelines for the production of labeled compounds used in regulatory studies. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures, typically between 2°C and 8°C (refrigerated) or as specified on the label and COA, to maintain stability and specific activity. Store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	Solid or Solution (as specified)
Identification (HPLC/MS)	Conforms
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 95%
Specific Activity	~9 Ci/mmol (Contact for exact value)
Solvent	Specified on COA (e.g., Ethanol, Toluene)
Concentration	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.