Description

Desvenlafaxine Succinate is the succinate salt form of the active pharmaceutical ingredient desvenlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI). This high-purity compound is critical for ensuring the efficacy, safety, and batch-to-batch consistency of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antidepressant medications.

Application

• Active Pharmaceutical Ingredient (API) in antidepressant drug formulations.
• Pharmaceutical Intermediates for the synthesis of related chemical entities.
• Reference Standard for quality control and analytical method development in laboratories.
• Research & Development of novel therapeutic agents targeting neurotransmitter systems.
• Generic Drug Manufacturing for bioequivalent pharmaceutical products.
• Clinical Trial Material supply for Phase I-IV investigational studies.

Basic Information

Product Name	Desvenlafaxine Succinate
CAS No.	448904-47-0
Molecular Formula	C18H29NO6
Molecular Weight	355.43 g/mol
Synonyms	O-Desmethylvenlafaxine Succinate; Desvenlafaxine Hemisuccinate; Pristiq (Brand Name API); WY-45233; 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol Succinate; 1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol Succinate
EINECS	Contact for details

Quality Control

Our Desvenlafaxine Succinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.