Description

4-[(2,2,3,3-Tetrafluoropropoxy)Methyl]Benzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of a benzoic acid core with a tetrafluoropropoxy side chain, offering enhanced lipophilicity, metabolic stability, and electronic properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators where the fluorine moiety improves bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored surface properties, chemical resistance, and durability.
• Organic Synthesis Reagent: Employed in organic synthesis as a versatile acid component for esterification and amidation reactions to introduce fluorinated aromatic segments.
• Material Science Research: Utilized in R&D for developing novel organic electronic materials, coatings, and additives.

Basic Information

Product Name	4-[(2,2,3,3-Tetrafluoropropoxy)Methyl]Benzoic Acid
CAS No.	444151-68-2
Molecular Formula	C11H10F4O3
Molecular Weight	266.19 g/mol
Synonyms	Benzoic acid, 4-[(2,2,3,3-tetrafluoropropoxy)methyl]-; 4-[(Perfluoropropoxy)methyl]benzoic acid; p-[(2,2,3,3-Tetrafluoropropoxy)methyl]benzoic acid; 4-(2,2,3,3-Tetrafluoropropoxymethyl)benzoic acid; 4-Carboxybenzyl 2,2,3,3-tetrafluoropropyl ether; 444151-68-2; TFPMBA
EINECS	Contact for details

Quality Control

Our 4-[(2,2,3,3-Tetrafluoropropoxy)Methyl]Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.