Description

4-Chloro-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity nucleoside analog building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the creation of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the synthesis of experimental compounds targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool Compound: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism pathways.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Process Chemistry & Scale-Up: Sourced by fine chemical manufacturers for the pilot-scale and commercial-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Chloro-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	443642-33-9
Molecular Formula	C12H14ClN3O4
Molecular Weight	299.71 g/mol
Synonyms	4-Chloro-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-C-Methyl-4-chloropyrrolo[2,3-d]pyrimidine nucleoside; 4-Chloro-2'-C-methyl-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2'-methyl nucleoside analog; 443642-33-9; 4-Cl-2'-C-Me-ribofuranosyl-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.