Description

Tris(4,6-Dimethyl-3-Sulfanatophenyl)Phosphine Trisodium Salt Hydrate is a specialized, water-soluble phosphine ligand featuring sulfonate groups, which impart excellent solubility in aqueous systems. This compound is a critical catalyst component in transition metal-catalyzed reactions, enabling efficient processes in both organic and aqueous media. It is essential for researchers and manufacturers in the pharmaceutical, fine chemical, and advanced materials sectors who require robust, water-compatible catalytic systems for cross-coupling, hydrogenation, and other key synthetic transformations.

Application

• As a water-soluble ligand for aqueous-phase transition metal catalysis, including Suzuki, Heck, and Sonogashira cross-coupling reactions.
• Key component in catalyst systems for hydrogenation and hydroformylation reactions in environmentally friendly aqueous or biphasic media.
• Facilitates homogeneous catalysis in pharmaceutical intermediate synthesis, where product separation and catalyst recovery are crucial.
• Used in the development of advanced materials and polymers via metal-catalyzed polymerization techniques.
• Employed in academic and industrial R&D for exploring new catalytic methodologies in green chemistry.
• Potential use in bioconjugation chemistry and the functionalization of biomolecules.

Basic Information

Product Name	Tris(4,6-Dimethyl-3-Sulfanatophenyl)Phosphine Trisodium Salt Hydrate
CAS No.	443150-11-6
Molecular Formula	C24H27Na3O9PS3 • xH2O
Molecular Weight	Approx. 664.6 g/mol (anhydrous basis)
Synonyms	Tris(3-sulfo-4,6-dimethylphenyl)phosphine trisodium salt hydrate; Trisodium tris(4,6-dimethyl-3-sulfophenyl)phosphine hydrate; Sulfonated Tris(dimethylphenyl)phosphine trisodium salt; Water-soluble TPPTS analogue; 3,3',3''-Phosphanetriyltris(benzenesulfonic acid) trisodium salt derivative; Na3[P(C6H2(CH3)2-3-SO3)3] • xH2O; TPPTS-Me (common abbreviation)
EINECS	Contact for details

Quality Control

Our production of Tris(4,6-Dimethyl-3-Sulfanatophenyl)Phosphine Trisodium Salt Hydrate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high catalytic performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles. We operate under a quality management system and can provide material tailored to research or cGMP-grade requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture, which can affect performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 8.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Solubility (in Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.