Description

5-Bromo-2-Difluoromethoxy-Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the difluoromethoxy and bromo substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and liquid crystals, where the halogen and fluorine atoms modify material properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to pharmaceutical and biotechnology clients.

Basic Information

Product Name	5-Bromo-2-Difluoromethoxy-Benzoic Acid
CAS No.	438221-79-5
Molecular Formula	C8H5BrF2O3
Molecular Weight	267.03 g/mol
Synonyms	5-Bromo-2-(difluoromethoxy)benzoic acid; Benzoic acid, 5-bromo-2-(difluoromethoxy)-; 2-(Difluoromethoxy)-5-bromobenzoic acid; 5-Bromo-2-(difluoromethoxy)benzoic acid; 438221-79-5; 5-Br-2-OCF2H-benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Difluoromethoxy-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.