Description

3-Chloro-5-(Trifluoromethoxy)Benzoic Acid is a high-purity, multi-functional aromatic carboxylic acid building block, distinguished by its unique combination of chloro and trifluoromethoxy substituents. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical development. It is primarily sought by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic display and lighting materials.
• Polymer Modification: Incorporated as a monomer or additive to impart specific chemical resistance, thermal stability, or surface properties to high-performance polymers.
• Organic Synthesis & Catalysis: Employed as a versatile precursor in cross-coupling reactions, metal-organic framework (MOF) construction, and ligand design for catalysis.
• Chemical Research: A valuable reagent for academic and industrial research exploring structure-activity relationships and new synthetic methodologies.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethoxy)Benzoic Acid
CAS No.	433926-46-6
Molecular Formula	C8H4ClF3O3
Molecular Weight	240.56 g/mol
Synonyms	3-Chloro-5-(trifluoromethoxy)benzoic acid; Benzoic acid, 3-chloro-5-(trifluoromethoxy)-; 5-(Trifluoromethoxy)-3-chlorobenzoic acid; 3-Chloro-α,α,α-trifluoro-5-methoxybenzoic acid; 3-Chloro-5-trifluoromethoxybenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Trifluoromethoxy)Benzoic Acid is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and comprehensive analytical testing is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing specific results for each parameter is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.