Description

R-2,2'-Bis(Methoxymethoxy)-3,3'-Diphenyl-1,1'-Binaphthalene is a high-value, chiral binaphthyl derivative used as a sophisticated ligand and building block in asymmetric synthesis. This compound matters because it provides a rigid, three-dimensional framework essential for inducing high enantioselectivity in catalytic reactions, directly impacting the purity and efficacy of final products. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Asymmetric Catalysis: Serving as a privileged chiral ligand for transition metal complexes (e.g., Rh, Pd, Ru) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex, chiral active pharmaceutical ingredients (APIs) targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
• Material Science: A building block for chiral polymers, liquid crystals, and molecular recognition systems used in sensors and advanced optics.
• Academic & Industrial R&D: A valuable tool for methodology development in organic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	R-2,2'-Bis(Methoxymethoxy)-3,3'-Diphenyl-1,1'-Binaphthalene
CAS No.	428874-67-3
Molecular Formula	C38H32O4
Molecular Weight	552.66 g/mol
Synonyms	(R)-2,2'-Bis(methoxymethoxy)-3,3'-diphenyl-1,1'-binaphthalene; (R)-3,3'-Diphenyl-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; R-BINOL-DMOM-Ph; (R)-BINOL Derivative; R-3,3'-Diphenyl-BINOL-DMOM; Chiral Binaphthyl Ligand; (R)-DMOM-BINAPh; Asymmetric Synthesis Ligand
EINECS	Contact for details

Quality Control

Our R-2,2'-Bis(Methoxymethoxy)-3,3'-Diphenyl-1,1'-Binaphthalene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity, which is paramount for catalytic performance. Each lot is characterized by HPLC, NMR, and optical rotation analysis to confirm identity, chemical purity, and enantiomeric excess (ee). Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is stable under inert atmosphere. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.