Description

(R)-2-[(Diphenylphosphino)Methyl]Pyrrolidine, Min. 97% is a high-purity, chiral phosphine ligand essential for asymmetric synthesis. This compound matters because it enables precise control over stereochemistry in catalytic reactions, directly impacting the yield and purity of advanced pharmaceutical intermediates and fine chemicals. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel, enantiomerically pure compounds.

Application

• As a chiral ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions.
• For the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and key intermediates.
• In catalyst development and optimization for industrial-scale fine chemical production.
• As a critical reagent in academic and industrial research exploring new asymmetric methodologies.
• For the preparation of chiral catalysts used in agrochemical and fragrance manufacturing.

Basic Information

Product Name	(R)-2-[(Diphenylphosphino)Methyl]Pyrrolidine, Min. 97%
CAS No.	428514-91-4
Molecular Formula	C18H22NP
Molecular Weight	283.35 g/mol
Synonyms	(R)-(-)-2-(Diphenylphosphinomethyl)pyrrolidine; (R)-2-(Diphenylphosphanylmethyl)pyrrolidine; (R)-Pyrrolidine, 2-[(diphenylphosphino)methyl]-; (R)-2-(Diphenylphosphinomethyl)pyrrolidine; (R)-ProNOP; (R)-2-[(Diphenylphosphino)methyl]pyrrolidine; (R)-2-(DPPM)Pyrrolidine; (R)-DPPMP
EINECS	Contact for details

Quality Control

Our (R)-2-[(Diphenylphosphino)Methyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and consistent chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain purity and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.