Description

4,5-Difluoro-2-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of fluorine atoms and a methoxy group, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing fluorine-containing drug candidates for oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-methoxy benzoate structure can enhance biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic chemicals for display and lighting technologies, improving thermal stability and electro-optical properties.
• Organic Synthesis & Chemical Research: Employed as a versatile reagent in academic and industrial R&D for constructing complex fluorinated aromatic systems via coupling, esterification, and amidation reactions.
• Material Science Precursor: Utilized in the development of specialty polymers, coatings, and advanced materials requiring fluorinated aromatic components for enhanced performance characteristics.

Basic Information

Product Name	4,5-Difluoro-2-Methoxybenzoic Acid
CAS No.	425702-18-7
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-Methoxy-4,5-difluorobenzoic Acid; 4,5-Difluoro-2-methoxybenzoic Acid; 4,5-Difluoro-o-anisic Acid; Benzoic acid, 4,5-difluoro-2-methoxy-; 425702-18-7; 4,5-Difluoro-2-methoxy-benzoic acid; 2-Methoxy-4,5-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and production applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.