Description

2'-Cyano-2-Fluorobiphenyl-3-Ylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile intermediate for constructing complex molecules via cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly those requiring the specific biphenyl scaffold with fluorine and nitrile functional groups.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the stability and reactivity of the biphenyl core.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, including polymers for OLEDs and semiconductors.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to form carbon-carbon bonds, enabling the efficient construction of biaryl structures prevalent in many functional molecules.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysts or as a model substrate for catalyst screening and optimization.
• Chemical Biology Probes: Acts as a synthetic handle for creating molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	2'-Cyano-2-Fluorobiphenyl-3-Ylboronic Acid
CAS No.	425378-90-1
Molecular Formula	C₁₃H₉BFNO₂
Molecular Weight	241.03 g/mol
Synonyms	(2-Cyano-2'-fluorobiphenyl-3-yl)boronic acid; 2-Fluoro-2'-cyanobiphenyl-3-boronic acid; 3-Borono-2'-cyano-2-fluorobiphenyl; 2'-Cyano-2-fluorobiphenyl-3-boronic acid; 2-Fluoro-2'-cyanobiphenyl-3-ylboronic acid; (3-(2-Cyano-2-fluorophenyl)phenyl)boronic acid; B-(2-Cyano-2'-fluorobiphenyl-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2'-Cyano-2-Fluorobiphenyl-3-Ylboronic Acid undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and other relevant techniques, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.