Description

Benzoic Acid, 5-Amino-2,3-Difluoro-4-Hydroxy-, Methyl Ester (9Ci) is a high-value, multi-functional fluorinated benzoate derivative, serving as a critical synthetic intermediate. Its molecular structure, featuring amino, fluoro, and hydroxy substituents, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and advanced materials sectors, where precise chemical modification is required. The CAS number for this product is 420786-99-8.

Application

This specialized fluorinated intermediate is designed for high-value synthesis across several advanced industries:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving performance characteristics.
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating advanced, light-fast colorants and functional dyes.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	Benzoic Acid, 5-Amino-2,3-Difluoro-4-Hydroxy-, Methyl Ester (9Ci)
CAS No.	420786-99-8
Molecular Formula	C8H7F2NO3
Molecular Weight	203.14 g/mol
Synonyms	5-Amino-2,3-difluoro-4-hydroxybenzoic acid methyl ester; Methyl 5-amino-2,3-difluoro-4-hydroxybenzoate; 2,3-Difluoro-4-hydroxy-5-aminobenzoic acid methyl ester; 5-Amino-2,3-difluoro-4-hydroxy methyl benzoate; 420786-99-8 (CAS Registry Number); Benzoic acid, 5-amino-2,3-difluoro-4-hydroxy-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Amino-2,3-Difluoro-4-Hydroxy-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and propensity for oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.