Description

Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Methoxy-, (2S)- is a high-purity, chiral amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a methoxy substituent. This compound is a critical building block in modern organic synthesis, offering precise stereochemical control for the development of complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of peptides, peptidomimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in peptide-based therapeutics.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Agrochemical Research: Used in the synthesis of chiral ligands and complex molecules for crop protection agents.
• Chemical Biology & Proteomics: Employed in the design and synthesis of enzyme inhibitors, probes, and labeled compounds for biochemical studies.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and medicinal chemistry projects.
• Custom Synthesis: A starting material for the tailored production of more advanced, proprietary intermediates for clients.

Basic Information

Product Name	Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Methoxy-, (2S)-
CAS No.	412352-66-0
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	(2S)-3-[(tert-Butoxycarbonyl)amino]-2-methoxypropanoic acid; Boc-L-3-Amino-2-methoxypropionic acid; (S)-3-(Boc-amino)-2-methoxypropionic acid; 2-Methoxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid; N-Boc-3-amino-2-methoxy-(S)-propionic acid; Boc-Amp(OMe)-OH; Boc-β-homoSer(OMe)-OH
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.