Description

(2R)-1,4-Dioxane-2-Methanol CAS NO 406913-88-0 is a chiral, non-racemic derivative of 1,4-dioxane, serving as a valuable building block in asymmetric synthesis. Its significance lies in its ability to introduce chirality and functional groups into complex molecules, enabling the production of enantiomerically pure compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for transition metal catalysis, enabling enantioselective reactions.
• Agrochemical Synthesis: Employed in the research and production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Building Block: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating polymers with tailored properties.
• Academic & Industrial Research: Serves as a standard or starting material in methodological development for organic and medicinal chemistry.

Basic Information

Product Name	(2R)-1,4-Dioxane-2-Methanol
CAS No.	406913-88-0
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	(R)-1,4-Dioxane-2-methanol; (2R)-1,4-Dioxan-2-ylmethanol; (R)-(+)-1,4-Dioxane-2-methanol; (R)-2-(Hydroxymethyl)-1,4-dioxane; 1,4-Dioxane-2-methanol, (2R)-; (R)-1,4-Dioxane-2-ylmethanol; (2R)-2-(Hydroxymethyl)-1,4-dioxane; (R)- enantiomer of 1,4-Dioxane-2-methanol
EINECS	Contact for details

Quality Control

Our (2R)-1,4-Dioxane-2-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.