Description

6,7-Difluoronaphthalene-1-Carboxylic Acid is a high-purity fluorinated naphthalene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms and carboxylic acid group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system and oncological pathways.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the difluoro motif enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure for creating fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Employed to introduce fluorine-containing aromatic units into specialty polymers, improving their thermal and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterification, and amide bond formation for constructing complex polycyclic aromatic systems.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	6,7-Difluoronaphthalene-1-Carboxylic Acid
CAS No.	405196-36-3
Molecular Formula	C₁₁H₆F₂O₂
Molecular Weight	208.16 g/mol
Synonyms	1-Naphthalenecarboxylic acid, 6,7-difluoro-; 6,7-Difluoro-1-naphthoic acid; 6,7-Difluoronaphthalene-1-carboxylic acid; 6,7-Difluoro-1-naphthalenecarboxylic acid; 1-Carboxy-6,7-difluoronaphthalene; DFNCA; 405196-36-3 (CAS)
EINECS	Contact for details

Quality Control

Our 6,7-Difluoronaphthalene-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.