Description

Telaprevir CAS NO 402957-28-2 is a potent and selective small-molecule inhibitor of the hepatitis C virus (HCV) NS3/4A serine protease. This compound is a critical active pharmaceutical ingredient (API) used in the development of antiviral therapies, representing a significant advancement in the treatment of chronic HCV genotype 1 infection. It is essential for pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in antiviral drug formulation and advanced clinical research.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of antiviral medications for the treatment of Hepatitis C Virus (HCV) infection.
• Pharmaceutical Research & Development: A key reference standard and intermediate in the discovery and development of next-generation protease inhibitor therapies.
• Clinical Trial Materials: Sourced for use in manufacturing drug products for Phase I-III clinical studies.
• Antiviral Mechanism Studies: Used in biochemical and virological assays to study HCV protease inhibition and viral replication kinetics.
• Generic Drug Manufacturing: Serves as the core API for companies producing generic versions of telaprevir-based treatments.
• Academic Research: Utilized in university and institutional labs for virology and medicinal chemistry research programs.

Basic Information

Product Name	Telaprevir
CAS No.	402957-28-2
Molecular Formula	C₃₆H₅₃N₇O₆
Molecular Weight	679.85 g/mol
Synonyms	VX-950; LY-570310; Telaprevirum; 1S,3aR,6aS)-(2-{3-[(2S)-2-({(1S,3aR,6aS)-2-[(2S)-2-cyclohexyl-2-(pyrazin-2-ylcarbonylamino)acetyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]octahydrocyclopenta[c]pyrrol-4-yl}formamido)-3,3-dimethylbutanoyl]-1H-imidazol-4-yl}-1,3,3a,4,5,6,6a,7,8,9-decahydrocyclopenta[4,5]pyrrolo[1,2-a]azepin-8-yl)boronic acid; INCIVEK; Telavic
EINECS	Contact for details

Quality Control

Our Telaprevir is manufactured under strict quality systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to ensure batch-to-batch consistency and regulatory compliance for research and production use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.