Description

R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative widely recognized for its utility as a sophisticated ligand and catalyst precursor in asymmetric synthesis. Its importance stems from its rigid, three-dimensional structure, which provides exceptional stereochemical control in critical bond-forming reactions. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to produce enantiomerically pure intermediates and active ingredients.

Application

• As a chiral ligand for transition metal-catalyzed asymmetric reactions, including hydrogenation, C-C bond formation, and oxidation.
• As a key precursor for constructing complex, enantioselective organocatalysts.
• In the research and development of novel active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• For the synthesis of advanced agrochemicals and specialty fine chemicals with specific stereochemistry.
• In academic and industrial research focused on developing new methodologies in asymmetric catalysis.
• As a resolving agent or chiral auxiliary in the separation and synthesis of enantiomers.

Basic Information

Product Name	R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	400027-51-2
Molecular Formula	C40H44O2
Molecular Weight	556.78 g/mol
Synonyms	(R)-H8-BINOL-TM; (R)-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-1,1'-Binaphthyl-2,2'-Diol; (R)-H8-3,3'-Mesityl-BINOL; (R)-5,5',6,6',7,7',8,8'-Octahydro-3,3'-di(2,4,6-trimethylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; R-H8-BINOL(Mes); R-3,3'-Dimesityl-H8-BINOL; (R)-H8-3,3'-(2,4,6-Trimethylphenyl)-BINOL
EINECS	Contact for details

Quality Control

Our production of R-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Bis(2,4,6-Trimethylphenyl)-[1,1'-Binaphthalene]-2,2'-Diol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.