Description

5H-Dibenzo(A,D)Cyclohepten-10-Ol, 10,11-Dihydro-5-(3-(Methylamino)Propylidene)-, (Z)- is a high-purity, structurally defined organic compound of significant interest in advanced chemical synthesis. This molecule serves as a critical pharmaceutical intermediate and a versatile building block for research and development. It is primarily sought after by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents.

Application

• Key Intermediate in Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules.
• Neurological & Psychiatric Drug Research: Used in the research and development of compounds targeting central nervous system (CNS) disorders.
• Medicinal Chemistry & Lead Optimization: Provides a sophisticated scaffold for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Reference Standard for Analytical Testing: Used as a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, GC).
• Academic & Institutional Research: Supports investigative studies in organic synthesis and pharmacology at universities and research institutes.

Basic Information

Item	Details
Product Name	5H-Dibenzo(A,D)Cyclohepten-10-Ol, 10,11-Dihydro-5-(3-(Methylamino)Propylidene)-, (Z)-
CAS No.	47132-19-4
Molecular Formula	C19H21NO
Molecular Weight	279.38 g/mol
Synonyms	(Z)-10,11-Dihydro-5-(3-(methylamino)propylidene)-5H-dibenzo[a,d]cyclohepten-10-ol; (Z)-Amitriptyline N-Oxide Impurity; (Z)-Desmethylamitriptyline N-Oxide; (Z)-Desmethyl-Nortriptyline N-Oxide; (Z)-10-Hydroxy-10,11-dihydro-5-(3-(methylamino)propylidene)-5H-dibenzo[a,d]cycloheptene; Nortriptyline Impurity F (Z-isomer); Amitriptyline Related Compound F
EINECS	Contact for details

Quality Control

Our production of 5H-Dibenzo(A,D)Cyclohepten-10-Ol, 10,11-Dihydro-5-(3-(Methylamino)Propylidene)-, (Z)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for pharmaceutical R&D use. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.