Description

Viloxazine CAS NO 46817-91-8 is a selective norepinephrine reuptake inhibitor (NRI) and a key pharmaceutical intermediate. Its primary commercial value lies in its critical role in the synthesis of the active pharmaceutical ingredient (API) for the treatment of attention deficit hyperactivity disorder (ADHD). This compound is essential for manufacturers in the pharmaceutical industry engaged in the production of central nervous system (CNS) therapeutics.

Application

• Primary Pharmaceutical Intermediate: The principal application is as a key building block in the synthesis of the Viloxazine hydrochloride API.
• ADHD Medication Production: Used in the manufacturing of prescription medications for the management of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric and adult patients.
• CNS Drug Research: Serves as a crucial reference standard and intermediate in research and development (R&D) for novel central nervous system agents.
• Generic Pharmaceutical Manufacturing: A vital raw material for generic drug manufacturers producing bioequivalent versions of branded ADHD treatments.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs and CDMOs specializing in the production of high-potency APIs (HPAPIs) and finished dosage forms.
• Analytical Standard: Utilized as a high-purity standard in Quality Control (QC) laboratories for method development, validation, and routine testing of final drug products.

Basic Information

Product Name	Viloxazine
CAS No.	46817-91-8
Molecular Formula	C13H19NO2
Molecular Weight	221.30 g/mol
Synonyms	Viloxazine (Base); 2-[(2-Ethoxyphenoxy)methyl]morpholine; (±)-Viloxazine; DL-Viloxazine; SP-1; Vivalan; ICI 58,834; EMD 33,043; 1-Morpholin-2-yl-2-(2-ethoxyphenoxy)ethanol (tautomeric form)
EINECS	Contact for details

Quality Control

Our Viloxazine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, purity, and consistency for your critical manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.