Description

(R)-(+)-1-(4-Bromophenyl)Ethylamine is a high-purity chiral amine building block, essential for the synthesis of enantiomerically pure pharmaceuticals and advanced materials. Its value lies in its role as a versatile intermediate for introducing a chiral center and a bromoaryl moiety into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and receptor-targeted therapies.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed reactions, including hydrogenation and cross-coupling.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of chiral polymers, liquid crystals, and advanced organic frameworks.
• Chemical Biology & Proteomics: Useful for creating chiral probes, affinity labels, and modifiers for studying enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high optical purity and reliable supply.

Basic Information

Product Name	(R)-(+)-1-(4-Bromophenyl)Ethylamine
CAS No.	45791-36-4
Molecular Formula	C8H10BrN
Molecular Weight	200.08 g/mol
Synonyms	(R)-(+)-1-(4-Bromophenyl)ethylamine; (R)-1-(4-Bromophenyl)ethanamine; (R)-4'-Bromo-α-methylbenzylamine; (R)-α-Methyl-4-bromobenzylamine; (R)-(+)-p-Bromo-α-methylbenzylamine; (R)-1-(p-Bromophenyl)ethylamine; (R)-4-Bromo-α-methylbenzylamine; (R)-(-)-1-(4-Bromophenyl)ethylamine (enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(4-Bromophenyl)Ethylamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high optical purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.