Description

4-Hydroxy-4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is a high-value biphenyl derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its molecular structure, featuring both a carboxylic acid and a trifluoromethyl-substituted aromatic ring, makes it an essential building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for the synthesis of fluorinated biphenyl cores used in high-performance liquid crystal displays (LCDs).
• Organic Electronic Materials: Employed in the research of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Complex Ligand Synthesis: Utilized in organometallic chemistry to create specialized ligands for catalysis and material science applications.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical companies producing bespoke compounds for client projects.

Basic Information

Product Name	4-Hydroxy-4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid
CAS No.	43029-72-7
Molecular Formula	C14H9F3O3
Molecular Weight	282.22 g/mol
Synonyms	3'-Carboxy-4-hydroxy-4'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-3-carboxylic acid, 4-hydroxy-4'-(trifluoromethyl)-; 4-Hydroxy-4'-trifluoromethylbiphenyl-3-carboxylic acid; 4'-Trifluoromethyl-4-hydroxybiphenyl-3-carboxylic acid; Biphenyl-3-carboxylic acid, 4-hydroxy-4'-trifluoromethyl-; 4-Hydroxy-4'-(trifluoromethyl)-1,1'-biphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-4'-Trifluoromethyl-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.