Description

2',3'-Dideoxy-2',3'-Didehydroinosine is a synthetic nucleoside analogue of significant interest in pharmaceutical research and development. This compound serves as a key intermediate and reference standard in the synthesis and study of antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving nucleoside kinases and polymerases.
• Antiviral Agent Development: Investigated for its potential activity against a range of viral targets due to its dideoxy-didehydro structure, which can act as a chain terminator.
• Academic Research: Employed in universities and research labs for studying nucleic acid metabolism, enzyme mechanisms, and structure-activity relationships (SAR).
• Process Development: Serves as a key material for scaling up synthetic routes and optimizing manufacturing processes for advanced therapeutic ingredients (ATIs).

Basic Information

Product Name	2',3'-Dideoxy-2',3'-Didehydroinosine
CAS No.	42867-68-5
Molecular Formula	C10H12N4O4
Molecular Weight	252.23 g/mol
Synonyms	2',3'-Dideoxy-2',3'-didehydroinosine; d4Inosine; 2',3'-Didehydro-2',3'-dideoxyinosine; 9-[(2R,5S)-5-(Hydroxymethyl)-2,5-dihydrofuran-2-yl]-9H-purin-6-ol; Inosine, 2',3'-dideoxy-2',3'-didehydro-; NSC 614312; ddIno
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxy-2',3'-Didehydroinosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.