Description

10,11-Dihydro-N,n-Dimethyl-5-Methylene-5H-Dibenzo[A,D]Cycloheptene-10-Ethanamine Maleate (1:1) is a high-purity pharmaceutical intermediate and active ingredient salt, supplied under strict quality control protocols. This compound is critical for ensuring the efficacy and consistency of downstream pharmaceutical formulations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry for the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing.
• Preclinical & Clinical Research: Serves as a critical material in pharmacological studies and drug discovery programs.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the final synthesis stages for commercial drug production under GMP conditions.
• Chemical Synthesis: Utilized in organic chemistry research for the construction of dibenzocycloheptene-based molecular frameworks.

Basic Information

Product Name	10,11-Dihydro-N,n-Dimethyl-5-Methylene-5H-Dibenzo[A,D]Cycloheptene-10-Ethanamine Maleate (1:1)
CAS No.	42834-51-5
Molecular Formula	C22H25NO4
Molecular Weight	367.44 g/mol
Synonyms	Nortriptyline Maleate; Nortriptyline Hydrochloride Maleate Salt; 5-(3-Methylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene maleate; Desmethylamitriptyline Maleate; 10,11-Dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-δ5,γ-propylamine maleate; Avantyl Maleate; Pamelor Maleate; Allegron Maleate
EINECS	Contact for details

Quality Control

Our 10,11-Dihydro-N,n-Dimethyl-5-Methylene-5H-Dibenzo[A,D]Cycloheptene-10-Ethanamine Maleate (1:1) is manufactured and tested to meet stringent quality standards suitable for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant pharmacopeial guidelines (e.g., USP, EP) where applicable, and custom synthesis under cGMP is available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.