Description

10-[2-(Dimethylamino)Ethyl]-5H-Dibenz[B,F]Azepine is a high-purity, advanced pharmaceutical intermediate with a complex tricyclic dibenzazepine core. This compound is valued for its critical role as a key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily required by research institutions and manufacturers in the global pharmaceutical and life sciences sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tricyclic antidepressant and antipsychotic drug candidates.
• Neurological Research: Used in medicinal chemistry research for developing compounds that interact with neurotransmitter systems.
• API Synthesis: Serves as a core structural unit in multi-step synthetic routes for complex active pharmaceutical ingredients.
• Chemical Reference Standard: Employed as a high-purity standard in analytical method development and quality control laboratories.
• Process Development: Utilized in scale-up and optimization studies for new pharmaceutical manufacturing processes.

Basic Information

Item	Details
Product Name	10-[2-(Dimethylamino)Ethyl]-5H-Dibenz[B,F]Azepine
CAS No.	41972-85-4
Molecular Formula	C₁₈H₂₀N₂
Molecular Weight	264.37 g/mol
Synonyms	10-(2-Dimethylaminoethyl)-5H-dibenzo[b,f]azepine; 5H-Dibenz[b,f]azepine, 10-[2-(dimethylamino)ethyl]-; 10-(2-Dimethylaminoethyl)dibenz[b,f]azepine; NSC 113927; 10-(2-(Dimethylamino)ethyl)-5H-dibenzo[b,f]azepine; 10-(β-Dimethylaminoethyl)-5H-dibenzo[b,f]azepine; 10-[2-(N,N-Dimethylamino)ethyl]-5H-dibenzo[b,f]azepine
EINECS	Contact for details

Quality Control

Our 10-[2-(Dimethylamino)Ethyl]-5H-Dibenz[B,F]Azepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.