Description

(2S)-2-Isopropylpyrrolidine is a high-purity, chiral pyrrolidine derivative, a versatile building block prized for its stereochemical integrity and nucleophilic nitrogen center. This compound is essential for the synthesis of complex molecules where precise spatial orientation is critical for biological activity or material properties. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and as a precursor for novel amine-based therapeutics.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective synthesis in fine chemical and pharmaceutical manufacturing.
• Agrochemical Synthesis: Serves as a building block for creating novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for methodological studies in organic synthesis and the exploration of new reaction pathways.
• Specialty Polymer Modification: Employed to introduce chiral amine functionalities into polymers, potentially altering their physical properties or creating chiral stationary phases for chromatography.

Basic Information

Product Name	(2S)-2-Isopropylpyrrolidine
CAS No.	41720-99-4
Molecular Formula	C7H15N
Molecular Weight	113.20 g/mol
Synonyms	(S)-2-Isopropylpyrrolidine; (S)-(-)-2-Isopropylpyrrolidine; L-2-Isopropylpyrrolidine; (2S)-2-(1-Methylethyl)pyrrolidine; (S)-2-(Propan-2-yl)pyrrolidine; (S)-α-Isopropylpyrrolidine; 2-Isopropylpyrrolidine, (S)-; Pyrrolidine, 2-(1-methylethyl)-, (2S)-
EINECS	Contact for details

Quality Control

Our (2S)-2-Isopropylpyrrolidine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.