Description

Adenosine-15N is a stable isotope-labeled analog of adenosine, where the nitrogen atoms are enriched with the 15N isotope. This product is essential for advanced research requiring precise metabolic tracing and quantification in biological systems using techniques like NMR spectroscopy and mass spectrometry. It is a critical material for pharmaceutical R&D, academic research in biochemistry and molecular biology, and the development of diagnostic assays.

Application

• Metabolic Pathway Tracing: Used as a tracer in NMR and LC-MS studies to elucidate adenosine metabolism, nucleotide synthesis, and energy transfer pathways (e.g., ATP cycle).
• Pharmaceutical Research: Serves as an internal standard for the quantitative bioanalysis of adenosine and its derivatives in drug metabolism and pharmacokinetics (DMPK) studies.
• Enzymology Studies: Employed in assays to study the kinetics and mechanisms of enzymes like adenosine deaminase, kinases, and nucleoside phosphorylases.
• Cardiovascular & Neurological Research: Investigates the role of adenosine signaling in conditions such as ischemia, inflammation, and sleep regulation.
• Diagnostic Development: Used in the development and calibration of clinical mass spectrometry assays for accurate measurement of adenosine levels in patient samples.
• Biomarker Discovery: Facilitates the discovery and validation of purine-based biomarkers in various disease states.

Basic Information

Product Name	Adenosine-15N
CAS No.	41547-82-4
Molecular Formula	C10H1315N5O4
Molecular Weight	Contact for details
Synonyms	9-β-D-Ribofuranosyladenine-15N5; Adenine riboside-15N5; 6-Amino-9-β-D-ribofuranosyl-9H-purine-15N5; 15N5-Adenosine; Adenosine (nitrogen-15); Stable Isotope Labeled Adenosine
EINECS	Contact for details

Quality Control

Our Adenosine-15N is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, with critical parameters verified by NMR, HPLC, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing purity, isotopic abundance, and analytical results, supporting research reproducibility and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
15N Isotopic Enrichment	≥ 98 atom % 15N
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.