Description

4-Fluoro-n-(1-Piperidinylmethyl)Benzohydroxamic Acid is a specialized hydroxamic acid derivative that serves as a critical building block and research chemical in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a piperidinylmethyl side chain, makes it a valuable scaffold for developing novel bioactive compounds. This high-purity intermediate is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating new therapeutic agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting metalloenzymes, such as histone deacetylases (HDACs) and matrix metalloproteinases (MMPs).
• Biochemical Research: Used as a reference standard and active probe in enzymatic studies and inhibitor screening assays within academic and industrial laboratories.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of potential therapeutic molecules.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for agrochemical and material science applications.
• Chemical Biology Tool: Utilized in the development of activity-based probes (ABPs) for profiling enzyme function and activity in biological systems.

Basic Information

Product Name	4-Fluoro-n-(1-Piperidinylmethyl)Benzohydroxamic Acid
CAS No.	40890-94-6
Molecular Formula	C13H17FN2O2
Molecular Weight	252.29 g/mol
Synonyms	4-Fluoro-N-[(piperidin-1-yl)methyl]benzohydroxamic acid; 4-Fluoro-N-(piperidin-1-ylmethyl)benzohydroxamic acid; 4-Fluoro-N-(1-piperidinylmethyl)benzhydroxamic acid; Benzohydroxamic acid, 4-fluoro-N-[(1-piperidinyl)methyl]-; 40890-94-6; N-[(1-Piperidinyl)methyl]-4-fluorobenzohydroxamic acid; 4-Fluoro-N-(piperidinomethyl)benzohydroxamic acid
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-n-(1-Piperidinylmethyl)Benzohydroxamic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.